Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532036 | 1.00 | HRH4 (0.62) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL11529676 | 1.00 | HRH4 (0.62) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL11529810 | 0.95 | HRH4 (0.59) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL11529766 | 0.88 | HRH4 (0.49) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL10747074 | 0.84 | HRH4 (0.84) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL9259496 | 0.84 | HRH4 (0.84) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL10748421 | 0.84 | HRH4 (0.84) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL9637156 | 0.84 | HRH4 (0.84) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL7353249 | 0.83 | HRH4 (0.66) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL11525991 | 0.83 | HRH4 (0.66) | HRH4HRH3LMNASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4157343-A | Preparation of aromatic diamines | UOP INC. (US) | 1979-06-05 | — | — | US | disclosed |