Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532194 | 0.91 | BCL2 (0.39) | OPRM1DRD3DRD2GRIN2DGRIN1 | |
| SCHEMBL11531667 | 0.87 | CES2 (0.38) | OPRM1DRD3DRD2GRIN2DGRIN1 | |
| SCHEMBL11533371 | 0.84 | SMN1; SMN2 (0.38) | CYP2C19HIF1APKMSMN1; SMN2KMT2A | |
| SCHEMBL11530455 | 0.80 | BCL2 (0.37) | SMN1; SMN2KMT2AMAPTHSD11B1MEN1 | |
| SCHEMBL11534465 | 0.79 | CES1 (0.47) | CYP2C19HIF1APKMSMN1; SMN2KMT2A | |
| SCHEMBL11532465 | 0.78 | MAPT (0.39) | CYP2C19HIF1APKMSMN1; SMN2KMT2A | |
| SCHEMBL11533841 | 0.78 | CYP2C9 (0.42) | SMN1; SMN2KMT2AMAPTLMNAL3MBTL1 | |
| SCHEMBL11532022 | 0.76 | KMT2A (0.40) | KMT2ACES2CES1MEN1POLB | |
| SCHEMBL11531767 | 0.75 | LMNA (0.45) | OPRM1DRD3DRD2GRIN2DGRIN1 | |
| SCHEMBL11530653 | 0.73 | CES1 (0.43) | CYP2C19KMT2ACES2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |