Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540604 | 0.85 | KMT2A (0.42) | KMT2ACYP3A4LMNATDP1 | |
| SCHEMBL11534505 | 0.80 | KMT2A (0.48) | CYP19A1KMT2ACYP3A4CYP3A5 | |
| SCHEMBL11542036 | 0.80 | KMT2A (0.51) | KMT2ALMNATDP1 | |
| SCHEMBL11534295 | 0.76 | KMT2A (0.66) | CYP19A1KMT2A | |
| SCHEMBL11537049 | 0.74 | KMT2A (0.45) | CYP19A1KMT2ACYP3A4CYP3A5 | |
| SCHEMBL11531936 | 0.73 | MEN1 (0.48) | CYP19A1KMT2ACYP3A4LMNA | |
| SCHEMBL11535928 | 0.72 | KMT2A (0.49) | KMT2ACYP3A4LMNATDP1 | |
| SCHEMBL11531547 | 0.72 | KMT2A (0.77) | CYP19A1KMT2ACYP3A4CYP3A5 | |
| SCHEMBL4055564 | 0.71 | KMT2A (0.57) | CYP19A1KMT2A | |
| SCHEMBL8243325 | 0.71 | KMT2A (0.57) | CYP19A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152441-A | Analgesic imidazolemethanols | GIST-BROCADES N.V. (NL) | 1979-05-01 | — | — | US | disclosed |