Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542036 | 0.94 | KMT2A (0.51) | KMT2ALMNATDP1GAASMN1; SMN2 | |
| SCHEMBL11535928 | 0.81 | KMT2A (0.49) | KMT2ALMNATDP1GAASMN1; SMN2 | |
| SCHEMBL11534505 | 0.80 | KMT2A (0.48) | KMT2AGAASMN1; SMN2KIF11ALDH1A1 | |
| Bromide SCHEMBL29033816 | 0.72 | LMNA (0.41) | LMNATDP1GAASMN1; SMN2CYP3A4 | |
| SCHEMBL11534499 | 0.66 | KCNH2 (0.40) | KMT2ALMNAALDH1A1MEN1POLB | |
| SCHEMBL12123082 | 0.65 | LMNA (0.60) | KMT2ALMNATDP1GAASMN1; SMN2 | |
| SCHEMBL11534295 | 0.64 | KMT2A (0.66) | KMT2ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL19418810 | 0.62 | LMNA (0.37) | LMNATDP1GAASMN1; SMN2CYP3A4 | |
| SCHEMBL36575 | 0.61 | — | — | |
| Bromide SCHEMBL28390663 | 0.60 | LMNA (0.42) | LMNATDP1GAASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152441-A | Analgesic imidazolemethanols | GIST-BROCADES N.V. (NL) | 1979-05-01 | — | — | US | disclosed |