Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542036 | 0.87 | KMT2A (0.51) | KMT2AGAASMN1; SMN2MEN1ATM | |
| SCHEMBL11540604 | 0.81 | KMT2A (0.42) | KMT2AGAASMN1; SMN2MEN1LMNA | |
| SCHEMBL11534505 | 0.79 | KMT2A (0.48) | KMT2AGAASMN1; SMN2MEN1ATM | |
| SCHEMBL11534280 | 0.75 | KMT2A (0.47) | KMT2AGAAMEN1ATMNPSR1 | |
| SCHEMBL11535538 | 0.66 | CYP19A1 (0.51) | KMT2AATMCFTRGOPCTDP1 | |
| SCHEMBL20866508 | 0.63 | KMT2A (0.59) | KMT2AMEN1ATMACSS2 | |
| SCHEMBL11591149 | 0.62 | CRHBP (0.53) | KMT2AMEN1ATMLMNACFTR | |
| SCHEMBL11533042 | 0.61 | KMT2A (0.46) | KMT2ASMN1; SMN2MEN1ATMLMNA | |
| SCHEMBL11531547 | 0.60 | KMT2A (0.77) | KMT2AMEN1MAPK1ACSS2CYP3A4 | |
| SCHEMBL26606321 | 0.60 | ALDH1A1 (0.46) | KMT2AGAAMAPK1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152441-A | Analgesic imidazolemethanols | GIST-BROCADES N.V. (NL) | 1979-05-01 | — | — | US | disclosed |