Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533481 | 1.00 | GRM6 (0.34) | GRM6MEN1LMNAKMT2APDK1 | |
| SCHEMBL11536002 | 0.86 | GRM6 (0.37) | GRM6KMT2ABCHE | |
| SCHEMBL11534640 | 0.84 | GAA (0.41) | KMT2ABCHE | |
| SCHEMBL11531879 | 0.83 | BCHE (0.38) | GRM6BCHE | |
| SCHEMBL11534917 | 0.80 | BCHE (0.42) | LMNABCHE | |
| SCHEMBL11530555 | 0.80 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL11530434 | 0.80 | KDM4E (0.42) | LMNABCHE | |
| SCHEMBL11440895 | 0.80 | MAPT (0.36) | GRM6LMNABCHE | |
| SCHEMBL11447544 | 0.80 | GRM6 (0.33) | GRM6 | |
| SCHEMBL11532072 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141883-A | Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives | SANKYO COMPANY, LIMITED (JP) | 1979-02-27 | — | — | US | disclosed |
| US-4075165-A | 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |