SCHEMBL11536002

SCHEMBL11536002

CCC1(C)CC(OC(C)=O)C(C)C(C)(CC)N1Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GRM6 O15303 1/20 0.37
BCHE P06276 1/20 0.37
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.36
AMPD2 Q01433 1/20 0.35
UBE2M P61081 1/20 0.35
DCUN1D1 Q96GG9 1/20 0.35
BRD4 O60885 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11534640 0.89 GAA (0.41) BCHETSHRKMT2A
SCHEMBL11531879 0.88 BCHE (0.38) GRM6BCHETSHR
SCHEMBL11533475 0.86 GRM6 (0.34) GRM6BCHEKMT2A
SCHEMBL11533481 0.86 GRM6 (0.34) GRM6BCHEKMT2A
SCHEMBL11534917 0.85 BCHE (0.42) BCHETSHR
SCHEMBL11530555 0.84 SIGMAR1 (0.35)
SCHEMBL11440895 0.84 MAPT (0.36) GRM6BCHETSHR
SCHEMBL11530434 0.84 KDM4E (0.42) BCHE
SCHEMBL11447544 0.84 GRM6 (0.33) GRM6
SCHEMBL11532967 0.83 GAA (0.38) TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4141883-A Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives SANKYO COMPANY, LIMITED (JP) 1979-02-27 US disclosed
US-4075165-A 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL CIBA-GEIGY CORPORATION (US) 1978-02-21 US disclosed