Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526082 | 0.94 | CHRM1 (0.53) | CHRM1HRH1PAK1 | |
| SCHEMBL11531754 | 0.88 | CHRM1 (0.70) | CHRM1HRH1PAK1 | |
| SCHEMBL11530525 | 0.83 | DRD2 (0.51) | CHRM1HRH1PAK1 | |
| SCHEMBL11531624 | 0.83 | CHRM1 (0.54) | CHRM1HRH1PAK1 | |
| SCHEMBL11536476 | 0.82 | CHRM1 (0.51) | CHRM1HRH1PAK1HRH4 | |
| SCHEMBL11527558 | 0.80 | CHRM1 (0.49) | CHRM1HRH1PAK1 | |
| SCHEMBL11532513 | 0.80 | HRH4 (0.49) | CHRM1HRH1HRH4 | |
| SCHEMBL9373916 | 0.76 | CHRM1 (0.48) | CHRM1HRH1PAK1HRH4 | |
| SCHEMBL11532012 | 0.74 | CHRM1 (0.66) | CHRM1HRH1PAK1HRH4 | |
| SCHEMBL11528431 | 0.72 | CHRM1 (0.64) | CHRM1HRH1PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172831-A | CENTRAL NERVOUS SYSTEM | LILLY INDUSTRIES LIMITED (GB) | 1979-10-30 | — | — | US | disclosed |
| US-4115574-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
| US-4115568-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |