Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20780369 | 0.84 | ALDH1A1 (0.40) | ALDH1A1GAAKMT2ACA12CA1 | |
| SCHEMBL970144 | 0.74 | CHRNB2 (0.38) | ALDH1A1GAAKMT2ACA12CA1 | |
| SCHEMBL965052 | 0.72 | CA12 (0.43) | ALDH1A1GAAKMT2ACA12CA1 | |
| SCHEMBL22222448 | 0.72 | CA1 (0.35) | ALDH1A1GAACA1MAPT | |
| SCHEMBL967637 | 0.71 | ALDH1A1 (0.42) | ALDH1A1GAAKMT2ACA12CA9 | |
| SCHEMBL966404 | 0.68 | ALDH1A1 (0.40) | ALDH1A1GAAKMT2ACHRNB2CHRNB4 | |
| SCHEMBL3276345 | 0.66 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2ACA12CA1 | |
| SCHEMBL21310488 | 0.66 | ALDH1A1 (0.35) | ALDH1A1GAACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11412957 | 0.65 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2ACHRNB2CHRNB4 | |
| SCHEMBL970247 | 0.65 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2ACHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137305-A | TOBACCO | WILKINSON SWORD LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4137304-A | TOPICAL OR ORAL ADMINISTERED TOBACCO PRODUCT | WILKINSON SWORD LIMITED (GB) | 1979-01-30 | — | — | US | disclosed |
| US-4136164-A | FOR USE IN FOODS, TOPICAL PREPARATIONS, AND TOBACCO | WILKINSON SWORD LIMITED (GB) | 1979-01-23 | — | — | US | disclosed |