Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | BACE1 | P56817 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17967915 | 0.84 | MEN1 (0.44) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL10334149 | 0.83 | KDM4E (0.75) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL23178593 | 0.83 | KDM4E (0.43) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL8352314 | 0.83 | SIGMAR1 (0.59) | KDM4EMEN1KMT2AALDH1A1BCHE | |
| Hydrochloric Acid SCHEMBL11537371 | 0.82 | SIGMAR1 (0.57) | KDM4EMEN1KMT2AALDH1A1BCHE | |
| SCHEMBL9832407 | 0.82 | KDM4E (0.81) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL6939806 | 0.81 | SIGMAR1 (0.49) | KDM4EMEN1KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL8310001 | 0.81 | KDM4E (0.67) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL16884170 | 0.80 | POLB (0.82) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL4108356 | 0.80 | BACE1 (0.44) | KDM4EMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138492-A | FOR TREATMENT OF GASTROINTESTINAL DISORDERS | ANPHAR, S.A. (ES) | 1979-02-06 | — | — | US | disclosed |