Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11167202 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4EUSP2MAPTHPGD | |
| SCHEMBL426292 | 0.81 | KDM4E (0.72) | ALDH1A1KDM4EAKR1B1USP2CSNK2A2 | |
| SCHEMBL11251461 | 0.81 | KDM4E (0.68) | ALDH1A1KDM4EAKR1B1USP2CSNK2A2 | |
| SCHEMBL10486553 | 0.81 | TNKS (0.61) | KDM4EMAPTTP53CYP3A4SMN1; SMN2 | |
| SCHEMBL8584061 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTTDP1HPGD | |
| SCHEMBL12829683 | 0.79 | CYP3A4 (0.50) | ALDH1A1KDM4EAKR1B1MAPTHPGD | |
| SCHEMBL12829688 | 0.79 | CYP3A4 (0.50) | ALDH1A1KDM4EAKR1B1MAPTHPGD | |
| SCHEMBL11244993 | 0.79 | KDM4E (0.65) | ALDH1A1KDM4EAKR1B1USP2CSNK2A2 | |
| SCHEMBL9847179 | 0.78 | KDM4E (0.67) | ALDH1A1KDM4EAKR1B1USP2CSNK2A2 | |
| SCHEMBL9847137 | 0.77 | KDM4E (0.66) | ALDH1A1KDM4EAKR1B1USP2CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133889-A | ANAPHYLAXIS ANTAGONISTS | FISONS, LTD. (GB) | 1979-01-09 | — | — | US | disclosed |