Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834789 | 0.95 | KDM4E (0.60) | KDM4EALDH1A1TDP1LMNAGPR35 | |
| SCHEMBL11827832 | 0.94 | KDM4E (0.58) | KDM4EALDH1A1TDP1LMNAGPR35 | |
| SCHEMBL11182177 | 0.93 | KDM4E (0.60) | KDM4EALDH1A1TDP1LMNAGPR35 | |
| SCHEMBL11458488 | 0.92 | KDM4E (0.56) | KDM4EALDH1A1TDP1LMNAGPR35 | |
| SCHEMBL9847179 | 0.91 | KDM4E (0.67) | KDM4EALDH1A1TDP1LMNAGPR35 | |
| SCHEMBL11339840 | 0.91 | KDM4E (0.60) | KDM4EALDH1A1TDP1LMNAGPR35 | |
| SCHEMBL11843063 | 0.90 | KDM4E (0.54) | KDM4EALDH1A1TDP1LMNAGPR35 | |
| SCHEMBL11058733 | 0.90 | GPR35 (0.58) | KDM4EALDH1A1TDP1LMNAGPR35 | |
| SCHEMBL11240996 | 0.89 | GPR35 (0.79) | KDM4EALDH1A1TDP1LMNAGPR35 | |
| SCHEMBL11467868 | 0.88 | ALDH1A1 (0.55) | KDM4EALDH1A1TDP1LMNAGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152448-A | ANTIINFLAMMATORY | FISONS LIMITED (GB) | 1979-05-01 | — | — | US | claimed |
| US-4362742-A | TOPICAL APPLICATION | SULLIVAN THOMAS J | 1982-12-07 | — | — | US | disclosed |
| US-4271182-A | TOPICAL APPLICATION OF 1,3-BIS((2-CARBOXY-CHROMON-5-)OXY)-2-HYDROXYPROPANE | FISONS LIMITED (GB) | 1981-06-02 | — | — | US | disclosed |
| US-4161516-A | PELLET OR GRANULAR, ADAPTED TO BE FLUIDIZE AND USED AS INHALANT | FISONS LIMITED (GB) | 1979-07-17 | — | — | US | disclosed |
| US-4152448-A | ANTIINFLAMMATORY | FISONS LIMITED (GB) | 1979-05-01 | — | — | US | disclosed |