Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530446 | 0.85 | MAPK1 (0.40) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL11528878 | 0.84 | MAPK1 (0.42) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL11529366 | 0.83 | MAPK1 (0.50) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL11529953 | 0.82 | MAPK1 (0.41) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL11527235 | 0.79 | MAPK1 (0.40) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL8715405 | 0.79 | CYP3A4 (0.40) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL11529051 | 0.77 | MAPK1 (0.34) | MAPK1TDP1CYP3A4TRPA1 | |
| SCHEMBL11533396 | 0.77 | MAPK1 (0.41) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL11535132 | 0.73 | MAPK1 (0.40) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL11528700 | 0.72 | TDP1 (0.37) | MAPK1TDP1CYP3A4TRPA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140792-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |