Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956658 | 0.88 | CYP3A4 (0.39) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL1020679 | 0.82 | TDP1 (0.47) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL11529051 | 0.81 | MAPK1 (0.34) | CYP3A4MAPK1TDP1TRPA1 | |
| SCHEMBL10968171 | 0.80 | CYP3A4 (0.48) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL10967067 | 0.80 | CYP3A4 (0.44) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL11535287 | 0.79 | CYP3A4 (0.42) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL11533832 | 0.79 | MAPK1 (0.36) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL10361851 | 0.76 | ALDH1A1 (0.30) | CYP3A4TDP1LMNA | |
| SCHEMBL11529366 | 0.75 | MAPK1 (0.50) | CYP3A4TSHRMAPK1TDP1TRPA1 | |
| SCHEMBL11622432 | 0.74 | CYP3A4 (0.45) | CYP3A4TSHRMAPK1TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750499-A4 | CARBANILIDE ANTICOCCIDIALS | LILLY CO ELI (US) | 1998-02-04 | — | — | EP | disclosed |
| EP-0750499-A1 | CARBANILIDE ANTICOCCIDIALS | ELI LILLY AND COMPANY (US) | 1997-01-02 | — | — | EP | disclosed |
| US-5541224-A | ANIMAL FEEDS | ELI LILLY AND COMPANY (US) | 1996-07-30 | — | — | US | disclosed |
| WO-1995024900-A1 | CARBANILIDE ANTICOCCIDIALS | ELI LILLY AND COMPANY (US) | 1995-09-21 | — | — | WO | disclosed |
| EP-0050827-B1 | 3-(P-ALKYLSULFONYLPHENYL)-AND 3-(P-ALKYLSULFINYLPHENYL)OXAZOLIDINONE DERIVATIVES AS ANTI-BACTERIAL AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4340606-A | 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-20 | — | — | US | disclosed |
| EP-0050827-A1 | 3-(p-Alkylsulfonylphenyl)-and 3-(p-alkylsulfinylphenyl)oxazolidinone derivatives as anti-bacterial agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-05-05 | — | — | EP | disclosed |
| US-4140792-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |