Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | FLT1 | P17948 | 2/20 | 0.51 |
| ▸ | FLT4 | P35916 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540950 | 0.79 | CA1 (0.67) | KMT2AMEN1MAPTFLT1FLT4 | |
| SCHEMBL420204 | 0.79 | MAPT (0.48) | KMT2AMEN1MAPTFLT1FLT4 | |
| SCHEMBL13485852 | 0.77 | CA1 (0.64) | MAPTFLT1FLT4KDRCA1 | |
| SCHEMBL2371778 | 0.73 | FLT1 (0.49) | KMT2AMEN1MAPTFLT1FLT4 | |
| SCHEMBL416745 | 0.73 | FLT1 (0.53) | KMT2AMEN1MAPTFLT1FLT4 | |
| SCHEMBL644292 | 0.73 | VCAM1 (0.64) | KMT2AMEN1FLT1FLT4KDR | |
| SCHEMBL15787094 | 0.72 | APEX1 (0.62) | KMT2ARAB9A | |
| SCHEMBL7580420 | 0.72 | MAPT (0.62) | KMT2AMEN1MAPTHDAC1HDAC8 | |
| SCHEMBL11534302 | 0.72 | POLB (0.79) | KMT2AMEN1MAPTCA12CA1 | |
| SCHEMBL9487105 | 0.71 | MEN1 (0.62) | KMT2AMEN1MAPTFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133832-A | Blowing agents -bis(hydrocarbylsulfonyl) carbohydrazides | UNIROYAL, INC. (US) | 1979-01-09 | — | — | US | disclosed |
| US-4096100-A | Blowing agents-bis(hydrocarbylsulfonyl) carbohydrazides | UNIROYAL, INC. (US) | 1978-06-20 | — | — | US | disclosed |