Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.67 |
| ▸ | CA2 | P00918 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11293996 | 0.89 | POLB (0.69) | POLBLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL9131405 | 0.88 | POLB (0.79) | POLBLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL21861384 | 0.86 | POLB (0.65) | POLBLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL125338 | 0.85 | POLB (0.73) | POLBLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL11512561 | 0.83 | POLB (0.71) | POLBLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL7627224 | 0.83 | ALDH1A1 (0.72) | POLBLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL11535648 | 0.82 | GAA (0.76) | POLBLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL18322586 | 0.82 | KMT2A (0.73) | POLBLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL38663094 | 0.81 | KMT2A (0.71) | POLBLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL10122132 | 0.81 | LMNA (0.58) | POLBLMNAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133832-A | Blowing agents -bis(hydrocarbylsulfonyl) carbohydrazides | UNIROYAL, INC. (US) | 1979-01-09 | — | — | US | disclosed |
| US-4096100-A | Blowing agents-bis(hydrocarbylsulfonyl) carbohydrazides | UNIROYAL, INC. (US) | 1978-06-20 | — | — | US | disclosed |