SCHEMBL11533964

SCHEMBL11533964

C[C@H](NC(=O)C(F)(F)F)C(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.39
RECQL P46063 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
XBP1 P17861 2/20 0.39
NPSR1 Q6W5P4 4/20 0.38
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CA14 Q9ULX7 2/20 0.37
MAPK1 P28482 1/20 0.37
ATM Q13315 1/20 0.37
CTSK P43235 1/20 0.37
CA12 O43570 1/20 0.37
POLB P06746 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11533969 1.00 MAPT (0.39) MAPTRECQLTDP1XBP1NPSR1
SCHEMBL11537134 1.00 MAPT (0.39) MAPTRECQLTDP1XBP1NPSR1
SCHEMBL8944922 0.82 CA14 (0.43) MAPTRECQLALDH1A1MEN1KMT2A
SCHEMBL6446520 0.81 PSENEN (0.41) TDP1NPSR1ALDH1A1CA14CTSK
SCHEMBL2555385 0.81 MAPT (0.39) MAPTRECQLTDP1XBP1NPSR1
SCHEMBL30170109 0.79 CA14 (0.36) TDP1NPSR1CA14CTSKPOLB
SCHEMBL21488593 0.78 CA2 (0.34) ALDH1A1POLBCA2
SCHEMBL24796325 0.78 CA12 (0.40) MAPTRECQLTDP1XBP1NPSR1
SCHEMBL23607312 0.78 CA1 (0.52) MAPTNPSR1KMT2ACA14CTSK
SCHEMBL23849248 0.78 CA1 (0.52) MAPTNPSR1KMT2ACA14CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-02 US disclosed
EP-4056580-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND COMPRISING HIGHLY STERICALLY HINDERED AMINO ACID CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-09-14 EP disclosed
US-4140496-A GAS CHROMATOGRAPHY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-02-20 US disclosed
US-4104040-A Use of s-triazine derivatives in a gas chromatographic method SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid DNPEP, VIP, NPEPPS MAPT 2810/4885RECQL 4867/4885TDP1 4557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.