Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632714 | 1.00 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3OPRD1OPRK1 | |
| SCHEMBL11536050 | 0.92 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3OPRD1OPRK1 | |
| SCHEMBL11194103 | 0.92 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3OPRD1OPRK1 | |
| SCHEMBL11194100 | 0.92 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3OPRD1OPRK1 | |
| SCHEMBL11632103 | 0.87 | OPRM1 (0.66) | OPRD1OPRK1OPRM1 | |
| SCHEMBL11535292 | 0.87 | OPRM1 (0.66) | OPRD1OPRK1OPRM1 | |
| SCHEMBL11534095 | 0.87 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3OPRD1OPRK1 | |
| SCHEMBL11534092 | 0.87 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3OPRD1OPRK1 | |
| SCHEMBL11633462 | 0.87 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL11533289 | 0.86 | OPRK1 (0.65) | OPRD1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150135-A | ANALGESICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-17 | — | — | US | claimed |
| US-4077954-A | ANALGESICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-03-07 | — | — | US | claimed |
| US-4077954-A | ANALGESICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-03-07 | — | — | US | disclosed |