Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | ACSS2 | Q9NR19 | 7/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533903 | 0.95 | AHR (0.43) | KMT2AAHRACSS2ALOX15BL3MBTL1 | |
| SCHEMBL11531933 | 0.92 | KMT2A (0.45) | KMT2AAHRACSS2CYP19A1CYP3A4 | |
| SCHEMBL11537324 | 0.90 | KMT2A (0.48) | KMT2AAHRACSS2MEN1RORC | |
| SCHEMBL11531498 | 0.84 | USP2 (0.41) | KMT2AAHRACSS2CYP19A1RORC | |
| SCHEMBL11531880 | 0.82 | KMT2A (0.47) | KMT2ACYP19A1ALOX15BL3MBTL1CYP3A4 | |
| SCHEMBL11536188 | 0.82 | CYP19A1 (0.41) | KMT2ACYP19A1KCNH2 | |
| SCHEMBL11534280 | 0.81 | KMT2A (0.47) | KMT2AACSS2CYP19A1MEN1ALDH1A1 | |
| SCHEMBL20866508 | 0.80 | KMT2A (0.59) | KMT2AACSS2MEN1 | |
| SCHEMBL11534499 | 0.78 | KCNH2 (0.40) | KMT2ACYP19A1MEN1KCNH2ALDH1A1 | |
| SCHEMBL11537386 | 0.77 | CYP19A1 (0.43) | KMT2AACSS2CYP19A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152441-A | Analgesic imidazolemethanols | GIST-BROCADES N.V. (NL) | 1979-05-01 | — | — | US | claimed |
| US-4152441-A | Analgesic imidazolemethanols | GIST-BROCADES N.V. (NL) | 1979-05-01 | — | — | US | disclosed |