Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ACSS2 | Q9NR19 | 9/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534182 | 0.81 | KMT2A (0.48) | KMT2AACSS2MEN1ALDH1A1CYP19A1 | |
| SCHEMBL11537324 | 0.81 | KMT2A (0.48) | KMT2AACSS2MEN1ATM | |
| SCHEMBL11537386 | 0.81 | CYP19A1 (0.43) | KMT2AACSS2MEN1ATMALDH1A1 | |
| SCHEMBL11531933 | 0.79 | KMT2A (0.45) | KMT2AACSS2ALDH1A1CYP19A1 | |
| SCHEMBL11534499 | 0.77 | KCNH2 (0.40) | KMT2AMEN1ALDH1A1NPSR1CYP19A1 | |
| SCHEMBL11536188 | 0.76 | CYP19A1 (0.41) | KMT2ACYP19A1 | |
| SCHEMBL11533903 | 0.76 | AHR (0.43) | KMT2AACSS2 | |
| SCHEMBL11531498 | 0.76 | USP2 (0.41) | KMT2AACSS2CYP19A1 | |
| SCHEMBL11535928 | 0.75 | KMT2A (0.49) | KMT2AACSS2MEN1ATMTDP1 | |
| SCHEMBL20866508 | 0.73 | KMT2A (0.59) | KMT2AACSS2MEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152441-A | Analgesic imidazolemethanols | GIST-BROCADES N.V. (NL) | 1979-05-01 | — | — | US | disclosed |