Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11473425 | 0.91 | ADRB2 (0.42) | KDM4ECYP2D6ADRB2ADRB1ADRA2A | |
| SCHEMBL11536748 | 0.90 | CA1 (0.42) | KDM4ECYP2D6ADRB2ADRB1ADRA2A | |
| SCHEMBL11480722 | 0.81 | ADRB2 (0.49) | ADRB2ADRB1ADRA2AADRA1DADRA1A | |
| SCHEMBL11354288 | 0.79 | ADRB1 (0.63) | KDM4ECYP2D6ADRB2ADRB1ADRA2A | |
| SCHEMBL11349295 | 0.79 | ADRB1 (0.63) | KDM4ECYP2D6ADRB2ADRB1ADRA2A | |
| SCHEMBL11481741 | 0.79 | ADRB2 (0.62) | KDM4ECYP2D6ADRB2ADRB1ADRA2A | |
| Hydrochloric Acid SCHEMBL11357232 | 0.78 | ADRB1 (0.64) | KDM4ECYP2D6ADRB2ADRB1ADRA2A | |
| Hydrochloric Acid SCHEMBL11538393 | 0.78 | ADRB2 (0.63) | KDM4ECYP2D6ADRB2ADRB1ADRA2A | |
| SCHEMBL10822414 | 0.74 | EPHX2 (0.47) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL10822418 | 0.74 | EPHX2 (0.47) | ALDH1A1CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140713-A | Phenylethanolamine therapeutic agents | ALLEN & HANBURYS LIMITED (GB) | 1979-02-20 | — | — | US | disclosed |