Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 11/20 | 0.70 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.70 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.52 |
| ▸ | AGER | Q15109 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11531075 | 0.99 | DRD4 (0.69) | DRD4HTR4ABCC8AGERDRD3 | |
| SCHEMBL16607301 | 0.88 | ALDH1A1 (0.64) | DRD4HTR4ABCC8AGERALDH1A1 | |
| SCHEMBL9021757 | 0.84 | HTR4 (0.71) | DRD4HTR4ABCC8AGERDRD3 | |
| SCHEMBL9021711 | 0.83 | HTR4 (0.66) | DRD4HTR4ABCC8AGER | |
| SCHEMBL593226 | 0.82 | HTR4 (1.00) | DRD4HTR4DRD3DRD2HTR3A | |
| SCHEMBL10486827 | 0.82 | DRD4 (0.55) | DRD4HTR4DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL534945 | 0.81 | HTR4 (0.98) | DRD4HTR4DRD3DRD2HTR3A | |
| SCHEMBL9021909 | 0.81 | HTR4 (0.72) | DRD4HTR4 | |
| SCHEMBL10486822 | 0.81 | HTR4 (0.73) | DRD4HTR4DRD3DRD2 | |
| SCHEMBL9022207 | 0.81 | HTR4 (0.59) | DRD4HTR4AGERDRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138492-A | FOR TREATMENT OF GASTROINTESTINAL DISORDERS | ANPHAR, S.A. (ES) | 1979-02-06 | — | — | US | disclosed |