Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.88 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531968 | 0.94 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL6090949 | 0.87 | CYP19A1 (0.64) | CYP19A1CYP3A4 | |
| SCHEMBL11533065 | 0.87 | CYP19A1 (0.66) | CYP19A1CNR1 | |
| SCHEMBL11532548 | 0.86 | CYP19A1 (0.85) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL11535325 | 0.84 | CYP19A1 (0.62) | CYP19A1 | |
| SCHEMBL11532100 | 0.84 | CYP19A1 (0.62) | CYP19A1CYP3A4 | |
| SCHEMBL11533232 | 0.84 | CYP19A1 (0.62) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL11537316 | 0.84 | CYP19A1 (0.62) | CYP19A1 | |
| SCHEMBL11863057 | 0.84 | CYP19A1 (0.61) | CYP19A1 | |
| SCHEMBL15263039 | 0.84 | CYP19A1 (0.61) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152441-A | Analgesic imidazolemethanols | GIST-BROCADES N.V. (NL) | 1979-05-01 | — | — | US | disclosed |