Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529794 | 0.89 | ALDH1A1 (0.48) | ALDH1A1LMNAATMHSD17B10MAPT | |
| SCHEMBL2950930 | 0.76 | FKBP1A (0.47) | ALDH1A1LMNAATMHSD17B10MAPT | |
| SCHEMBL16572388 | 0.70 | ALDH1A1 (0.68) | ALDH1A1LMNAPOLBNPC1MEN1 | |
| SCHEMBL17835877 | 0.70 | KDM4E (0.71) | ATMHSD17B10POLBMEN1KMT2A | |
| SCHEMBL2554004 | 0.70 | POLB (0.54) | ALDH1A1LMNAATMHSD17B10MAPT | |
| SCHEMBL23610052 | 0.70 | KDM4E (0.71) | ATMHSD17B10POLBMEN1KMT2A | |
| SCHEMBL1460360 | 0.70 | KDM4E (0.71) | ATMHSD17B10POLBMEN1KMT2A | |
| SCHEMBL4631795 | 0.70 | POLB (0.54) | ALDH1A1LMNAATMHSD17B10MAPT | |
| SCHEMBL11539203 | 0.70 | MEN1 (0.66) | ALDH1A1LMNAHSD17B10RAB9APOLB | |
| SCHEMBL5510459 | 0.70 | ALDH1A1 (0.68) | ALDH1A1LMNAPOLBNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155907-A | Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines | THE DOW CHEMICAL COMPANY (US) | 1979-05-22 | — | — | US | claimed |