Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30141977 | 0.83 | RAB9A (0.61) | ADRA2AADRA2BADRA2CCYP11B1CYP11B2 | |
| SCHEMBL4779549 | 0.83 | RAB9A (0.61) | ADRA2AADRA2BADRA2CCYP11B1CYP11B2 | |
| SCHEMBL28266009 | 0.83 | SMN1; SMN2 (0.49) | NOTUMADRA2AADRA2BADRA2CCYP11B1 | |
| Hydrochloric Acid SCHEMBL4778775 | 0.81 | RAB9A (0.59) | ADRA2AADRA2BADRA2CCYP11B1CYP11B2 | |
| SCHEMBL112422 | 0.80 | NCOA1 (0.63) | NCOA1NCOA3RAB9ATP53LMNA | |
| SCHEMBL30708901 | 0.80 | NOTUM (0.63) | NOTUMCYP11B2SMN1; SMN2RAB9ATP53 | |
| SCHEMBL4032281 | 0.80 | NOTUM (0.63) | NOTUMCYP11B2SMN1; SMN2RAB9ATP53 | |
| SCHEMBL6321993 | 0.78 | NCOA1 (0.61) | NCOA1NCOA3RAB9ATP53LMNA | |
| SCHEMBL10756496 | 0.78 | NCOA1 (0.61) | NCOA1NCOA3RAB9ATP53LMNA | |
| SCHEMBL28431579 | 0.78 | NCOA1 (0.61) | NCOA1NCOA3RAB9ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140853-A | Process for the preparation of aminopyridines | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |