Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542256 | 1.00 | CYP3A4 (0.38) | CYP3A4LMNAELANETRPM8HTT | |
| SCHEMBL11540044 | 0.85 | ELANE (0.35) | ELANE | |
| SCHEMBL11537406 | 0.84 | ELANE (0.37) | ELANE | |
| SCHEMBL11528025 | 0.83 | TRPM8 (0.48) | ELANETRPM8HTT | |
| SCHEMBL11528023 | 0.83 | TRPM8 (0.48) | ELANETRPM8HTT | |
| SCHEMBL11535507 | 0.82 | ELANE (0.49) | ELANE | |
| SCHEMBL11537403 | 0.82 | ELANE (0.37) | ELANE | |
| SCHEMBL11537091 | 0.81 | ELANE (0.37) | ELANE | |
| SCHEMBL11374453 | 0.80 | ELANE (0.36) | CYP3A4ELANE | |
| SCHEMBL11528434 | 0.80 | ELANE (0.36) | LMNAELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4143047-A | 2-SULFINYL AND 2-SULFONYL OXAZOLES | LILLY INDUSTRIES LIMITED (GB) | 1979-03-06 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |