Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533072 | 0.94 | ELANE (0.44) | ELANEMLYCD | |
| SCHEMBL11537091 | 0.87 | ELANE (0.37) | ELANE | |
| SCHEMBL11528434 | 0.85 | ELANE (0.36) | ELANEMLYCD | |
| SCHEMBL11374453 | 0.85 | ELANE (0.36) | ELANEMEN1KMT2ACYP1A2GAA | |
| SCHEMBL11531229 | 0.85 | MLYCD (0.40) | ELANEMLYCDMEN1KMT2ACYP1A2 | |
| SCHEMBL11537403 | 0.85 | ELANE (0.37) | ELANEMLYCD | |
| SCHEMBL11537406 | 0.85 | ELANE (0.37) | ELANEMLYCD | |
| SCHEMBL11529943 | 0.84 | ELANE (0.36) | ELANEMLYCD | |
| Isamoxole SCHEMBL637131 | 0.84 | MLYCD (0.42) | ELANEMLYCDMEN1KMT2A | |
| SCHEMBL11533009 | 0.84 | ALDH1A1 (0.45) | ELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4143047-A | 2-SULFINYL AND 2-SULFONYL OXAZOLES | LILLY INDUSTRIES LIMITED (GB) | 1979-03-06 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |