Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.48 |
| ▸ | KDM4A | O75164 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.48 |
| ▸ | TET3 | O43151 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261082 | 0.81 | TET2 (0.67) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL6054264 | 0.81 | TET2 (0.67) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL406554 | 0.79 | TET2 (0.52) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL4140782 | 0.79 | TET2 (0.52) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL14661635 | 0.79 | TET2 (0.52) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL9515485 | 0.79 | TET2 (0.52) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL16600629 | 0.75 | TET2 (0.48) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL14661753 | 0.73 | GPR84 (0.50) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL14661321 | 0.73 | GPR84 (0.50) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL14662505 | 0.73 | GPR84 (0.50) | TET2KDM4AKDM4CKDM2ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138577-A | 11-Deoxy-cis-4,5-didehydro-ω-aryl-PGF compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138573-A | 11-Deoxy-2,2-difluoro-ω-aryl-PGE compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138576-A | 11-Deoxy-2,2-difluoro-ω-aryl-PGF compounds | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-4126754-A | 11-Deoxy-cis-4,5-didehydro-ω-aryl-PGE compounds | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |