SCHEMBL406554

SCHEMBL406554

CC(C)CCC(O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 3/20 0.52
KDM4A O75164 2/20 0.52
KDM4C Q9H3R0 2/20 0.52
KDM2A Q9Y2K7 2/20 0.52
TET3 O43151 1/20 0.52
GPR84 Q9NQS5 3/20 0.50
FFAR1 O14842 1/20 0.50
OR51E2 Q9H255 1/20 0.46
TP53 P04637 1/20 0.45
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.43
BLM P54132 1/20 0.43
CA1 P00915 1/20 0.40
RNPEP Q9H4A4 1/20 0.39
CYP1A2 P05177 1/20 0.39
SLC7A5 Q01650 1/20 0.39
GABRR1 P24046 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14661635 1.00 TET2 (0.52) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL9515485 1.00 TET2 (0.52) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL3261082 0.85 TET2 (0.67) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL6054264 0.85 TET2 (0.67) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL14661633 0.84 GPR84 (0.58) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL3020360 0.84 GPR84 (0.58) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL16428981 0.84 GPR84 (0.58) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL28704367 0.84 GPR84 (0.64) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL4140782 0.83 TET2 (0.52) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL9446362 0.82 GPR84 (0.68) TET2KDM4AKDM4CKDM2ATET3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1059563-B1 Agent for reducing substrate dependence of resist WAKO PURE CHEM IND LTD (JP) 2006-08-09 EP claimed
JP-5000996-A None JP disclosed
JP-5000996-A None JP disclosed
JP-4217642-A None JP disclosed
US-20240397944-A1 METHODS FOR BIOFILM DISRUPTION Lixa Limited (AU) 2024-12-05 US disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
CN-105228993-B Compound and its purposes as spices 西姆莱斯股份公司 2018-02-13 CN disclosed
US-9115083-B2 Compounds from Antrodia cinnamomea and use thereof SIMPSON BIOTECH CO., LTD. (TW) 2015-08-25 US disclosed
US-9062028-B2 Bicyclic nitrogen containing heteroaryl TGR5 receptor modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2015-06-23 US disclosed
US-20150038333-A1 PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENT -RUN FÜR GESUNDHEIT UND (DE) 2015-02-05 US disclosed
US-5019615-A Polyphenylene ether/polyester blend with nitrodiamine compound SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1991-05-28 US disclosed
US-5017663-A Polyphenylene ether, polyamide blend SUMITOMO CHEMICAL CO., LTD. (JP) 1991-05-21 US disclosed
EP-0408255-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-16 EP disclosed
EP-0394016-A2 Resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-24 EP disclosed
EP-0391733-A2 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-10-10 EP disclosed
EP-0382548-A2 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-08-16 EP disclosed
EP-0381391-A2 Resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-08-08 EP disclosed
EP-0368283-A2 Resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-05-16 EP disclosed
EP-0176217-B1 PYROGLUTAMIC ACID ESTERS, THEIR SYNTHESIS AND USE IN TOPICAL PRODUCTS UNILEVER PLC (GB) 1989-06-07 EP disclosed
US-4514287-A MIXING WITH ALUMINUM SULFATE NIPPON OIL CO., LTD. (JP) 1985-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240397944-A1 METHODS FOR BIOFILM DISRUPTION FGB, MMP8, HAO2 TET2 464/4885KDM4A 1444/4885KDM4C 1003/4885
US-20150038333-A1 PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS HAO1, HAAO, HAO2 TET2 3904/4885KDM4A 4287/4885KDM4C 4247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.