Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602466 | 0.84 | KDM4C (0.53) | KDM4CALDH1A1HPGDNAALAD2GAA | |
| SCHEMBL9602462 | 0.84 | KDM4C (0.53) | KDM4CALDH1A1HPGDNAALAD2GAA | |
| SCHEMBL4135826 | 0.84 | KDM4C (0.53) | KDM4CALDH1A1HPGDNAALAD2HSD11B1 | |
| SCHEMBL13872406 | 0.83 | KDM4C (0.55) | KDM4CALDH1A1HPGDNAALAD2GAA | |
| SCHEMBL28695451 | 0.82 | KDM4C (0.51) | KDM4CALDH1A1HPGDNAALAD2GAA | |
| SCHEMBL18839933 | 0.82 | KDM4C (0.51) | KDM4CALDH1A1HPGDGAATRPV1 | |
| SCHEMBL3728791 | 0.79 | KDM4C (0.55) | KDM4CALDH1A1HPGDNAALAD2GAA | |
| SCHEMBL11802408 | 0.78 | KDM4C (0.48) | KDM4CALDH1A1HPGDMAPK1 | |
| SCHEMBL20223332 | 0.78 | KDM4C (0.54) | KDM4CALDH1A1HPGDGAATRPV1 | |
| SCHEMBL6952050 | 0.78 | KDM4C (0.54) | KDM4CALDH1A1HPGDNAALAD2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179511-A | Antibacterial 3-(5-tetrazolyl) penam compounds | PFIZER INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4143039-A | ANTIBACTERIAL 3-(5-TETRAZOLYL)PENAM COMPOUNDS | PFIZER INC. (US) | 1979-03-06 | — | — | US | disclosed |
| US-4115385-A | PENICILLINS | PFIZER INC. (US) | 1978-09-19 | — | — | US | disclosed |