Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135826 | 0.85 | KDM4C (0.53) | KDM4CALDH1A1HPGDNAALAD2MAPK1 | |
| SCHEMBL9602462 | 0.85 | KDM4C (0.53) | KDM4CALDH1A1HPGDNAALAD2MAPK1 | |
| SCHEMBL3728791 | 0.85 | KDM4C (0.55) | KDM4CALDH1A1HPGDCYP1A2NAALAD2 | |
| SCHEMBL11535261 | 0.84 | KDM4C (0.51) | KDM4CALDH1A1HPGDCYP1A2NAALAD2 | |
| SCHEMBL28695451 | 0.84 | KDM4C (0.51) | KDM4CALDH1A1HPGDNAALAD2MAPK1 | |
| SCHEMBL13872406 | 0.81 | KDM4C (0.55) | KDM4CALDH1A1HPGDNAALAD2MAPK1 | |
| SCHEMBL11802408 | 0.80 | KDM4C (0.48) | KDM4CALDH1A1HPGDMAPK1 | |
| SCHEMBL20223332 | 0.79 | KDM4C (0.54) | KDM4CALDH1A1HPGDMAPK1TRPV1 | |
| SCHEMBL6952050 | 0.79 | KDM4C (0.54) | KDM4CALDH1A1HPGDNAALAD2MAPK1 | |
| SCHEMBL10363667 | 0.79 | KDM4C (0.54) | KDM4CALDH1A1HPGDNAALAD2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |