Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 9/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535340 | 1.00 | LIG1 (0.38) | LIG1SLC6A2SLC6A4SLC6A3SLC6A9 | |
| SCHEMBL11539184 | 1.00 | LIG1 (0.38) | LIG1SLC6A2SLC6A4SLC6A3SLC6A9 | |
| SCHEMBL11187797 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3BACE1 | |
| SCHEMBL11534979 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3BACE1 | |
| SCHEMBL11187799 | 0.86 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3BACE1 | |
| SCHEMBL11247408 | 0.82 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3BACE1OPRK1 | |
| SCHEMBL11183844 | 0.77 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3OPRM1BACE1 | |
| SCHEMBL11539811 | 0.77 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3OPRM1BACE1 | |
| SCHEMBL11183841 | 0.77 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3OPRM1BACE1 | |
| SCHEMBL11252676 | 0.73 | SLC6A4 (0.55) | SLC6A2SLC6A4SLC6A3BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150135-A | ANALGESICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-17 | — | — | US | disclosed |