Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11572105 | 1.00 | SOAT1 (0.53) | SOAT1HDAC8LTA4HPTPN1PTPN11 | |
| SCHEMBL5991642 | 0.84 | SOAT1 (0.52) | SOAT1HDAC8LTA4HPTPN1PTPN11 | |
| SCHEMBL98132 | 0.84 | SOAT1 (0.52) | SOAT1HDAC8LTA4HPTPN1PTPN11 | |
| SCHEMBL39560 | 0.84 | SOAT1 (0.52) | SOAT1HDAC8LTA4HPTPN1PTPN11 | |
| SCHEMBL11535397 | 0.82 | SOAT1 (0.41) | SOAT1THRATHRBLTB4R | |
| SCHEMBL11536931 | 0.78 | BACE1 (0.54) | BACE1 | |
| SCHEMBL5988283 | 0.78 | BACE1 (0.53) | SOAT1HDAC8LTA4HPTPN1PTPN11 | |
| SCHEMBL14971446 | 0.75 | LTA4H (0.65) | LTA4H | |
| SCHEMBL6866588 | 0.73 | HDAC8 (0.55) | SOAT1HDAC8LTA4HPTPN1PTPN11 | |
| E319 SCHEMBL2009146 | 0.73 | ALDH1A1 (0.44) | SOAT1HDAC8PTPN1NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122270-A | ANTIOXIDANT | AKZONA INCORPORATED (US) | 1978-10-24 | — | — | US | claimed |
| US-4147659-A | HYDROXYPHENOXYTRIAZINES | AKZONA INCORPORATED (US) | 1979-04-03 | — | — | US | disclosed |
| US-4122270-A | ANTIOXIDANT | AKZONA INCORPORATED (US) | 1978-10-24 | — | — | US | disclosed |