Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12852295 | 0.86 | GAA (0.57) | ATMGAATDP1LMNAHPGD | |
| SCHEMBL12852314 | 0.85 | ATM (0.84) | ATMGAATDP1LMNACXCR4 | |
| SCHEMBL11536699 | 0.84 | ATM (0.67) | ATMGAATDP1LMNAHPGD | |
| SCHEMBL11535590 | 0.82 | HPGD (0.58) | ATMGAATDP1LMNAHPGD | |
| SCHEMBL11538782 | 0.81 | LMNA (0.62) | ATMGAATDP1LMNACXCR4 | |
| SCHEMBL12852303 | 0.80 | HPGD (0.47) | ATMLMNAHPGDALDH1A1MAPT | |
| SCHEMBL12682799 | 0.80 | ATM (1.00) | ATMLMNACXCR4MAPTPOLB | |
| SCHEMBL11536219 | 0.78 | CXCR4 (0.64) | ATMLMNACXCR4MAPTPOLB | |
| SCHEMBL11535652 | 0.75 | CXCR4 (0.60) | ATMGAATDP1LMNAHPGD | |
| SCHEMBL24441691 | 0.74 | HSD17B13 (0.60) | GAATDP1LMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | claimed |
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |