Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12852295 | 0.86 | GAA (0.57) | ATMUSP2KMT2AALDH1A1HTT | |
| SCHEMBL11538732 | 0.85 | POLB (0.64) | ATMUSP2KMT2AHTTLMNA | |
| SCHEMBL11535524 | 0.84 | ATM (0.67) | ATMUSP2KMT2AALDH1A1LMNA | |
| SCHEMBL11535590 | 0.82 | HPGD (0.58) | ATMKMT2AALDH1A1HTTLMNA | |
| SCHEMBL11538782 | 0.81 | LMNA (0.62) | ATMUSP2KMT2AALDH1A1LMNA | |
| SCHEMBL12682799 | 0.80 | ATM (1.00) | ATMUSP2HTTLMNAMAPT | |
| SCHEMBL11536912 | 0.78 | LMNA (0.61) | ATMUSP2KMT2AALDH1A1HTT | |
| SCHEMBL11535832 | 0.78 | ATM (0.59) | ATMUSP2KMT2AALDH1A1HTT | |
| SCHEMBL11537697 | 0.77 | ATM (0.61) | ATMUSP2KMT2AHTTLMNA | |
| SCHEMBL11535652 | 0.75 | CXCR4 (0.60) | ATMUSP2KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | claimed |
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |