Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535559 | 0.91 | KIF11 (0.40) | CYP3A4CYP2D6CYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL11535035 | 0.85 | KCNN4 (0.36) | KCNN4CYP11B1CYP11B2SIGMAR1TAAR1 | |
| SCHEMBL11533590 | 0.73 | CYP19A1 (0.51) | CYP11B1CYP11B2LMNACYP1A2CYP3A4 | |
| SCHEMBL11539766 | 0.70 | CYP11B1 (0.39) | KCNN4CYP11B1CYP11B2CYP3A4CYP2C19 | |
| SCHEMBL67163 | 0.69 | CYP2B6 (0.55) | LMNACYP3A4CYP2D6CYP2C19SIGMAR1 | |
| SCHEMBL30577371 | 0.69 | CYP11B1 (0.57) | KCNN4CYP11B1CYP11B2LMNACYP1A2 | |
| SCHEMBL11531667 | 0.68 | CES2 (0.38) | LMNACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8447048 | 0.68 | CHRM2 (0.42) | LMNASIGMAR1MEN1KMT2ACYP2B6 | |
| SCHEMBL11535596 | 0.67 | CYP11B1 (0.37) | KCNN4CYP11B1CYP11B2CYP3A4CYP2C19 | |
| SCHEMBL11535581 | 0.67 | OPRM1 (0.44) | KCNN4LMNACYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |