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SCHEMBL11535607

SCHEMBL11535607

CCC1(C)CC(OC(=O)c2cccc(C(=O)OC3CC(C)(CC)NC(C)(CC)C3C)c2)C(C)C(C)(CC)N1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.40
▸ UBE2D3 P61077 1/20 0.35
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ TSHR P16473 2/20 0.33
▸ BCHE P06276 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11467507 0.92 GAA (0.50) GAATSHRBCHE
SCHEMBL11536762 0.90 GAA (0.41) GAAMEN1KMT2AALDH1A1NPSR1
SCHEMBL11532371 0.87 TSHR (0.34) GAAALDH1A1TSHR
SCHEMBL11532490 0.85 CYP3A4 (0.31) GAA
SCHEMBL11536285 0.85 ALDH1A1 (0.42) GAAMEN1KMT2AALDH1A1NPSR1
SCHEMBL11531728 0.83 GAA (0.36) GAAMEN1KMT2AALDH1A1NPSR1
SCHEMBL11620915 0.82 HDAC3 (0.32) GAA
SCHEMBL11531928 0.81 LMNA (0.48) GAAALDH1A1TSHRBCHE
SCHEMBL11412814 0.81 CYP3A4 (0.49) GAAMEN1KMT2AALDH1A1TSHR
SCHEMBL11531267 0.81 LMNA (0.36) GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4141883-A Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives SANKYO COMPANY, LIMITED (JP) 1979-02-27 — — US disclosed