Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529180 | 0.92 | NPC1 (0.62) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL11543333 | 0.83 | NPSR1 (0.47) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL31359577 | 0.79 | MAPT (0.64) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL6870170 | 0.78 | ALDH1A1 (0.62) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL6780371 | 0.78 | NPC1 (0.59) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL13204575 | 0.77 | POLB (0.55) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL9128620 | 0.77 | MAPT (0.55) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL11535688 | 0.76 | ALDH1A1 (0.46) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL5215589 | 0.75 | CES2 (0.57) | MAPTPOLBNPC1RAB9AMEN1 | |
| SCHEMBL1791860 | 0.75 | MAPT (0.73) | MAPTPOLBNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141806-A | MULTISTAGE, TEMPERATURE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-27 | — | — | US | disclosed |
| US-4107012-A | COATINGS, PRINTING INKS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-15 | — | — | US | disclosed |