Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | AGER | Q15109 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | ASPH | Q12797 | 2/20 | 0.43 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10750671 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL10094225 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL15994461 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL7053365 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL14354346 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL11535213 | 0.76 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL27958570 | 0.75 | KDM4E (0.52) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL24912635 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL8802880 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL20509034 | 0.72 | KDM4E (0.49) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138488-A | Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138488-A | Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138488-A | Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |