Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | ASPH | Q12797 | 3/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467198 | 0.78 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL11535855 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL4686655 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPTALOX15TSHR | |
| SCHEMBL10750671 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL7119627 | 0.75 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL11859120 | 0.73 | SRC (0.39) | ALDH1A1MAPTALOX15TSHRCYP1A2 | |
| Bicarbonate SCHEMBL27706335 | 0.73 | CES2 (0.46) | ALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL5053925 | 0.73 | GSR (0.42) | ALDH1A1ALOX15TSHRCYP1A2LMNA | |
| SCHEMBL460268 | 0.71 | SLC6A2 (0.53) | KDM4EALDH1A1L3MBTL1CYP3A4TSHR | |
| SCHEMBL4687758 | 0.71 | ALDH1A1 (0.38) | ALDH1A1ALOX15TSHRCYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1308432-A1 | PROCESS FOR THE PREPARATION OF 5- (4-CHLOROPHENYL)-METHYL]-2,2-DIMETHYLCYCLOPENTANONE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2003-05-07 | — | — | EP | disclosed |
| WO-2003026664-A1 | 2-PHENYLAMINO-4- (5-PYRAZOLYLAMINO) -PYRAMIDINE DERIVATIVES AS KINASE INHIBITORS, IN PARTICULAR, SRC KINASE INHIBITORS | BAYER CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |