⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6632156 | 0.97 | — | — | |
| SCHEMBL24620217 | 0.91 | ALDH1A1 (0.30) | — | |
| SCHEMBL3774381 | 0.84 | — | — | |
| SCHEMBL696010 | 0.78 | — | — | |
| SCHEMBL12688314 | 0.77 | ALDH1A1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL1201605 | 0.76 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL28038248 | 0.76 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL345144 | 0.76 | — | — | |
| SCHEMBL4831827 | 0.74 | KEAP1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL1273427 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144743-A1 | COMPOUNDS | TMEM16A LIMITED (GB) | 2026-05-28 | — | — | US | disclosed |
| EP-4699655-A2 | COMPOUNDS | TMEM16A LIMITED (GB) | 2026-02-25 | — | — | EP | disclosed |
| EP-4628499-A1 | POLYPEPTIDE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2025-10-08 | — | — | EP | disclosed |
| US-12377105-B2 | Compounds | TMEM16A LIMITED (GB) | 2025-08-05 | — | — | US | disclosed |
| CN-114616226-B | Pyridine derivatives as TMEM16A modulators for the treatment of respiratory disorders | TMEM16A有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119490451-A | Compounds as positive modulators of calcium activated chloride channels | TMEM16A有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-111683926-B | Compounds of formula (I) | 企业治疗学有限公司 | 2024-11-08 | — | — | CN | disclosed |
| US-12037324-B2 | Biarylmethyl heterocycles | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| US-20240083917-A1 | Polycyclic Kinase Inhibitor | Xuanzhu Biopharmaceutical Co., Ltd. (CN) | 2024-03-14 | — | — | US | disclosed |
| EP-4289853-A1 | POLYCYCLIC KINASE INHIBITOR | Shandong Xuanzhu Pharma Co., Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| US-6271180-B2 | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| US-20010004629-A1 | Substituted phenyl keto enols as pesticides and herbicides | LIEB VOLKER (DE) | 2001-06-21 | — | — | US | disclosed |
| WO-2001019816-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |
| US-6140358-A | FOR CONTROLLING PESTS AND WEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-31 | — | — | US | disclosed |
| EP-1000036-A1 | HYDANTOIN DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE | LG CHEMICAL LIMITED (KR) | 2000-05-17 | — | — | EP | disclosed |
| US-5958936-A | FOR INDUCING ANTIANDROGENIC ACTIVITY IN WARM-BLOODED ANIMALS, INCLUDING HUMANS | HOECHST MARION ROUSSEL (FR) | 1999-09-28 | — | — | US | disclosed |
| WO-1999005117-A1 | HYDANTOIN DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE | LG CHEMICAL LTD. (KR) | 1999-02-04 | — | — | WO | disclosed |
| US-5705654-A | ANTIANDROGENS | ROUSSEL UCLAF (FR) | 1998-01-06 | — | — | US | disclosed |
| US-5646172-A | Method of inducing antiandrogenic activity using imidazolidines substituted with a heterocycle | ROUSSEL UCLAF (FR) | 1997-07-08 | — | — | US | disclosed |
| EP-0704448-A1 | Heterocyclic substituted imidazolidines, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1996-04-03 | — | — | EP | disclosed |