Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1472484 | 0.85 | KMT2A (0.55) | KMT2APOLBNR3C1GABRPGABRD | |
| SCHEMBL11796115 | 0.84 | KMT2A (0.57) | KMT2APOLBKDM4EALDH1A1TDP1 | |
| SCHEMBL1471838 | 0.78 | POLB (0.61) | KMT2APOLBPDE4B | |
| SCHEMBL7009102 | 0.72 | PDE4B (0.49) | KMT2AKDM4EALDH1A1TDP1NR3C1 | |
| SCHEMBL4339847 | 0.72 | POLB (0.49) | POLBPDE4B | |
| SCHEMBL11544175 | 0.72 | KMT2A (0.74) | KMT2APOLBNR3C1 | |
| SCHEMBL11602100 | 0.70 | KMT2A (0.43) | KMT2APOLBKDM4EALDH1A1TDP1 | |
| SCHEMBL11721689 | 0.70 | KMT2A (0.75) | KMT2APOLBKDM4EALDH1A1PDE4B | |
| SCHEMBL17963273 | 0.69 | NR3C1 (0.65) | NR3C1PDE4B | |
| SCHEMBL9838391 | 0.69 | NR3C1 (0.36) | NR3C1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153796-A | ANTIALLERGENS, BRONCHODILATOR AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-05-08 | — | — | US | disclosed |