Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471838 | 0.89 | POLB (0.61) | POLBPDE4B | |
| SCHEMBL4334216 | 0.81 | PDE4B (0.73) | PDE4B | |
| SCHEMBL4335330 | 0.77 | PDE4B (0.66) | PDE4B | |
| SCHEMBL4954967 | 0.75 | PDE1B (0.42) | — | |
| SCHEMBL4952368 | 0.75 | PDE1B (0.42) | — | |
| SCHEMBL582853 | 0.74 | PDE4B (0.82) | PDE4B | |
| SCHEMBL5962789 | 0.74 | POLB (0.52) | POLBPDE4B | |
| SCHEMBL4330507 | 0.74 | PDE4B (0.41) | POLBPDE4B | |
| SCHEMBL4339841 | 0.72 | PDE4B (0.53) | PDE4B | |
| SCHEMBL11536617 | 0.72 | KMT2A (0.44) | POLBPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539753-B1 | PYRAZOLO(3,4-B)PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2009-09-09 | — | — | EP | disclosed |