Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.65 |
| ▸ | AHR | P35869 | 4/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenoxazine SCHEMBL7862 | 0.81 | ALOX5 (1.00) | ALOX5HTR2BHTR7LMNAMAPT | |
| Phenoxazine SCHEMBL6310178 | 0.81 | ALOX5 (1.00) | ALOX5HTR2BHTR7LMNAMAPT | |
| Phenoxazine SCHEMBL29355714 | 0.81 | ALOX5 (1.00) | ALOX5HTR2BHTR7LMNAMAPT | |
| Phenoxazine SCHEMBL28844098 | 0.81 | ALOX5 (1.00) | ALOX5HTR2BHTR7LMNAMAPT | |
| SCHEMBL8725779 | 0.81 | ALOX5 (0.65) | ALOX5AHRHTR2BHTR7LMNA | |
| SCHEMBL6045366 | 0.81 | ALOX5 (0.65) | ALOX5AHRHTR2BHTR7LMNA | |
| Bicarbonate SCHEMBL6265391 | 0.81 | ALOX5 (0.56) | ALOX5HTR2BHTR7LMNATP53 | |
| Phenoxazine SCHEMBL25275195 | 0.79 | ALOX5 (0.94) | ALOX5HTR2BHTR7LMNAMAPT | |
| Phenoxazine SCHEMBL20840431 | 0.79 | ALOX5 (0.94) | ALOX5HTR2BHTR7LMNAMAPT | |
| Phenoxazine SCHEMBL5808288 | 0.79 | ALOX5 (0.94) | ALOX5HTR2BHTR7LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132794-A | 10-Imidoylacridan compositions | MEAD JOHNSON & COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4094981-A | SMOOTH MUSCLE RELAXANT EMPLOYING 10-IMIDOYLACRIDANS | MEAD JOHNSON & COMPANY (US) | 1978-06-13 | — | — | US | disclosed |
| US-4046891-A | Smooth muscle relaxant process employing 10-imidoylphenoxazines | MEAD JOHNSON & COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-3962252-A | 10-IMIDOYLACRIDANS | MEAD JOHNSON & COMPANY (US) | 1976-06-08 | — | — | US | disclosed |