Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.60 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4370497 | 0.87 | NPC1 (0.57) | KDM4EALDH1A1POLBL3MBTL1NR4A1 | |
| SCHEMBL1649243 | 0.87 | FOLH1 (0.68) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL131229 | 0.83 | FOLH1 (0.63) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL2532316 | 0.82 | ELANE (0.56) | KDM4EALDH1A1POLBL3MBTL1PTGER1 | |
| SCHEMBL4295650 | 0.82 | FOLH1 (0.62) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL25160011 | 0.81 | POLB (0.54) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL29151389 | 0.81 | POLB (0.54) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL3174029 | 0.81 | LMNA (0.56) | POLBL3MBTL1FOLH1NPC1RAB9A | |
| SCHEMBL551475 | 0.81 | FOLH1 (0.60) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL5485828 | 0.81 | SMPD1 (0.70) | KDM4EALDH1A1POLBL3MBTL1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160036-A | ADRENERGIC STIMULANTS | ALLEN & HANBURYS LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |