Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | RECQL | P46063 | 6/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | DBH | P09172 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA7 | P43166 | 4/20 | 0.51 |
| ▸ | CA9 | Q16790 | 4/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11290292 | 0.98 | KDM4E (0.65) | KDM4ERECQLGAADBHCA12 | |
| SCHEMBL4953998 | 0.85 | KDM4E (0.71) | KDM4ERECQLGAADBHCA12 | |
| SCHEMBL426484 | 0.85 | KDM4E (0.71) | KDM4ERECQLGAADBHCA12 | |
| SCHEMBL8471397 | 0.80 | KDM4E (1.00) | KDM4ERECQLGAADBHCA12 | |
| Hydrochloric Acid SCHEMBL11288312 | 0.79 | KDM4E (0.58) | KDM4ERECQLGAADBHCA12 | |
| SCHEMBL9658758 | 0.79 | CA1 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2988488 | 0.79 | KDM4E (0.74) | KDM4ERECQLGAADBHCA12 | |
| Hydrochloric Acid SCHEMBL6462448 | 0.77 | CA1 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8982946 | 0.77 | KDM4E (0.71) | KDM4ERECQLGAADBHCA12 | |
| SCHEMBL11288771 | 0.76 | ALOX15 (0.48) | KDM4ERECQLGAADBHCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147799-A | Process for reducing blood pressure and blocking β-adrenergic receptor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |