Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | RECQL | P46063 | 2/20 | 0.74 |
| ▸ | DBH | P09172 | 1/20 | 0.74 |
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA7 | P43166 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8471397 | 0.85 | KDM4E (1.00) | KDM4EGAARECQLDBHCA12 | |
| SCHEMBL30882518 | 0.82 | KDM4E (0.52) | KDM4EGAARECQLDBHCA12 | |
| SCHEMBL8982946 | 0.82 | KDM4E (0.71) | KDM4EGAARECQLDBHCA12 | |
| SCHEMBL4953998 | 0.82 | KDM4E (0.71) | KDM4EGAARECQLDBHCA12 | |
| SCHEMBL426484 | 0.82 | KDM4E (0.71) | KDM4EGAARECQLDBHCA12 | |
| SCHEMBL28052189 | 0.80 | MEN1 (0.66) | KDM4EGAARECQLDBHMAPT | |
| SCHEMBL21456599 | 0.79 | KDM4E (0.43) | KDM4EGAARECQLDBHCA12 | |
| SCHEMBL27833057 | 0.79 | KDM4E (0.62) | KDM4EGAARECQLDBHCA12 | |
| SCHEMBL9407168 | 0.79 | KDM4E (0.67) | KDM4EGAARECQLDBHCA12 | |
| SCHEMBL9407166 | 0.79 | KDM4E (0.67) | KDM4EGAARECQLDBHCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255228-A1 | Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles | BIODERM RESEARCH (US) | 2008-10-16 | — | — | US | claimed |
| US-20080254130-A1 | Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction | BIODERM RESEARCH (US) | 2008-10-16 | — | — | US | claimed |
| US-7427690-B2 | Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration | BIODERM RESEARCH (US) | 2008-09-23 | — | — | US | claimed |
| US-20070099886-A1 | Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration | BIODERM RESEARCH (US) | 2007-05-03 | — | — | US | claimed |
| US-20060074108-A1 | Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition | BIODERM RESEARCH (US) | 2006-04-06 | — | — | US | claimed |
| US-20050271608-A1 | Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives | GUPTA SHYAM K | 2005-12-08 | — | — | US | claimed |
| US-8227426-B2 | Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care | ISLAND KINETICS INC. (US) | 2012-07-24 | — | — | US | disclosed |
| US-20110059907-A1 | Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care | ISLAND KINETICS INC. (US) | 2011-03-10 | — | — | US | disclosed |
| US-7834210-B2 | Hair loss prevention by natural amino acid and peptide complexes | BIODERM RESEARCH (US) | 2010-11-16 | — | — | US | disclosed |
| US-7777073-B2 | Topical delivery system for antiaging and skin whitening agents | BIODERM RESEARCH (US) | 2010-08-17 | — | — | US | disclosed |
| US-20090253668-A1 | Hair Loss Prevention by Natural Amino Acid and Peptide Complexes | BIODERM RESEARCH (US) | 2009-10-08 | — | — | US | disclosed |
| US-7572933-B2 | Skin and hair restoration by natural amino acid peptide complexes | BIODERM RESEARCH (US) | 2009-08-11 | — | — | US | disclosed |
| US-20090130154-A1 | Topical Delivery of Biological and Cosmetic Agents by Zeolites | BIODERM RESEARCH (US) | 2009-05-21 | — | — | US | disclosed |
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | BIODERM RESEARCH (US) | 2009-03-19 | — | — | US | disclosed |
| US-20080287536-A1 | Skin and Hair Restoration by Natural Amino Acid and Peptide Crown Complexes | BIODERM RESEARCH (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080255228-A1 | Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles | BIODERM RESEARCH (US) | 2008-10-16 | — | — | US | disclosed |
| US-7427690-B2 | Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration | BIODERM RESEARCH (US) | 2008-09-23 | — | — | US | disclosed |
| US-20080139507-A1 | Method of Treating Skin Condition Including Acne, Skin Aging, Body Odor & Diaper Rash by Zinc Zeolite Clathrates | BIODERM RESEARCH (US) | 2008-06-12 | — | — | US | disclosed |
| US-20070099886-A1 | Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration | BIODERM RESEARCH (US) | 2007-05-03 | — | — | US | disclosed |
| US-3991139-A | NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059907-A1 | Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care | GLA, LPO, PLOD3 | KDM4E 1594/4885GAA 123/4885RECQL 1131/4885 |
| US-20090130154-A1 | Topical Delivery of Biological and Cosmetic Agents by Zeolites | TYR, MMP1, MMP17 | KDM4E 1764/4885GAA 31/4885RECQL 4058/4885 |
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | TYR, MMP17, MMP1 | KDM4E 1048/4885GAA 232/4885RECQL 1961/4885 |
| US-20080287536-A1 | Skin and Hair Restoration by Natural Amino Acid and Peptide Crown Complexes | MMP17, MC1R, TYR | KDM4E 1992/4885GAA 195/4885RECQL 2681/4885 |
| US-20080254130-A1 | Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction | PSMB1, PLOD3, CUTA | KDM4E 513/4885GAA 130/4885RECQL 1201/4885 |
| US-20090253668-A1 | Hair Loss Prevention by Natural Amino Acid and Peptide Complexes | MMP1, MMP17, MMP13 | KDM4E 3063/4885GAA 754/4885RECQL 2442/4885 |
| US-20080255228-A1 | Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles | PROC, COL1A1, CUTA | KDM4E 1689/4885GAA 365/4885RECQL 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.