Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PTPRA | P18433 | 2/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPRB | P23467 | 1/20 | 0.49 |
| ▸ | PTPRE | P23469 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988908 | 0.86 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10PTPN1PTPRA | |
| SCHEMBL1308628 | 0.83 | KDM4E (0.62) | KDM4EALDH1A1GLAGAAHSD17B10 | |
| SCHEMBL4371765 | 0.81 | PTPN1 (0.50) | KDM4EALDH1A1GLAGAAHSD17B10 | |
| SCHEMBL4361320 | 0.80 | PTPN1 (0.49) | KDM4EALDH1A1GLAGAAPTPN1 | |
| SCHEMBL4361861 | 0.80 | PTPN1 (0.76) | KDM4EALDH1A1GLAGAAPTPN1 | |
| SCHEMBL4365650 | 0.80 | PTPN1 (0.49) | KDM4EALDH1A1GLAGAAPTPN1 | |
| SCHEMBL11445926 | 0.78 | ALDH1A1 (0.56) | KDM4EALDH1A1GLAGAAHSD17B10 | |
| SCHEMBL30629527 | 0.78 | ALDH1A1 (0.56) | KDM4EALDH1A1GLAGAAHSD17B10 | |
| SCHEMBL5649788 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1GLAGAAHSD17B10 | |
| SCHEMBL4371772 | 0.76 | PTPN1 (0.49) | KDM4EALDH1A1PTPN1PTPRAPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154961-A | Oxamic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-05-15 | — | — | US | claimed |