SCHEMBL1308628

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3044265	0.86	KDM4E (0.71)	KDM4EALDH1A1GAAHSD17B10SERPINE1
	SCHEMBL11536873	0.83	KDM4E (0.63)	KDM4EALDH1A1GLAGAAHSD17B10
	SCHEMBL1309023	0.82	ALDH1A1 (0.50)	KDM4EALDH1A1GLAGAAMEN1
	SCHEMBL28534851	0.81	USP2 (0.55)	KDM4EALDH1A1GAAHPGDRAB9A
	SCHEMBL30661117	0.80	MAPT (0.64)	ALDH1A1GAASMN1; SMN2SERPINE1MAPT
	SCHEMBL19253255	0.80	MAPT (0.64)	ALDH1A1GAASMN1; SMN2SERPINE1MAPT
	SCHEMBL19268087	0.79	TP53 (0.54)	KDM4EALDH1A1HSD17B10KMT2ASMN1; SMN2
	SCHEMBL19268075	0.79	GABRP (0.63)	KDM4EALDH1A1HSD17B10RAB9ASMN1; SMN2
	SCHEMBL8766311	0.78	MEN1 (0.59)	ALDH1A1GAAMEN1KMT2ARAB9A
	SCHEMBL11445926	0.77	ALDH1A1 (0.56)	KDM4EALDH1A1GLAGAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.