Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6915697 | 0.97 | THRB (0.46) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL11538522 | 0.97 | THRB (0.43) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL11536932 | 0.94 | THRB (0.48) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL28234072 | 0.94 | THRB (0.39) | THRB | |
| SCHEMBL11542038 | 0.88 | THRB (0.42) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL15016766 | 0.85 | THRB (0.38) | THRB | |
| SCHEMBL11536909 | 0.77 | THRB (0.55) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL10421655 | 0.74 | THRB (0.59) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL7647628 | 0.74 | THRB (0.59) | THRBCA1CA2MMP1MMP2 | |
| SCHEMBL1608943 | 0.74 | THRB (0.30) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172016-A | Method for manufacture of perfluorotetrahydrofuran derivatives | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1979-10-23 | — | — | US | disclosed |